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More than 700 people have joined a Facebook group called "HGV Lorries Parked on Monument Way South Willesborough Must Go".
The group on the social networking website was created just over a fortnight ago.
Double yellow lines are due to be painted on the roads of Orbital Business Park this week in the hope that they will prevent lorry drivers parking at the business park and encourage them to use the official truckstop nearby instead.
Huge trucks block the vision of drivers and rubbish, including human waste, often litters area.