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Ashford United will start their new Bostik South season at home to Carshalton Athletic next month.
The Southern Counties East League Premier Division champions are one of 11 Kent clubs in the newly sponsored competition this season.
Herne Bay, with new joint-bosses John Embery and Jermaine Darlington now in charge, also begin at home against Lewes.
Sittingbourne travel to Chipstead.
Hythe Town host Walton Casuals, while Ramsgate meet Phoenix Sports, one of three clubs, together with VCD and Thamesmead Town, switched from the North division.
Faversham Town travel to VCD on the opening day, while Cray Wanderers meet Thamesmead.
Last season's beaten play-off semi-finalists Greenwich Borough begin at home to Whyteleafe.
August Bank Holiday Monday includes three Kent derbies as Faversham meet Herne Bay, Sittingbourne face Ashford, and Hythe host Ramsgate.
Opening Day Fixtures - Saturday August 12:
Ashford United v Carshalton Athletic
Chipstead v Sittingbourne
Cray Wanderers v Thamesmead Town
Greenwich Borough v Whyteleafe
Herne Bay v Lewes
Hythe Town v Walton Casuals
Ramsgate v Phoenix Sports
VCD Athletic v Faversham Town
August Bank Holiday Monday, August 28:
Faversham Town v Herne Bay
Greenwich Borough v Phoenix Sports
Hythe Town v Ramsgate
Shoreham v Cray Wanderers
Sittingbourne v Ashford United
VCD Athletic v Thamesmead Town
Boxing Day:
Ashford United v Sittingbourne
Cray Wanderers v Shoreham
Herne Bay v Faversham Town
Phoenix Sports v Greenwich Borough
Ramsgate v Hythe Town
Thamesmead Town v VCD Athletic
New Years Day:
Faversham Town v Ashford United
Greenwich Borough v Cray Wanderers
Hythe Town v Herne Bay
Shoreham v Thamesmead Town
Sittingbourne v. Ramsgate
VCD Athletic v Phoenix Sports
Final Day: Saturday, April 28
Ashford United v Walton Casuals
Carshalton Athletic v VCD Athletic
Hastings United v Sittingbourne
Herne Bay v Greenwich Borough
Hythe Town v Corinthian-Casuals
Molesey v Faversham Town
Phoenix Sports v Shoreham
Ramsgate v East Grinstead Town
Thamesmead Town v South Park