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Drivers travelling towards London are stuck in eight-mile-long queues following a crash involving a car and a lorry along the M25.
Motorists are facing 60-minute delays along the anti-clockwise carriageway on the approach to the Dartford Crossing.
This comes after a collision closed two lanes at the Thurrock junction just after 4.15pm.
The road was later cleared - but shortly afterwards a vehicle breakdown prompted the closure of the east bore tunnel.
A spokesman for Highways England South East warned: "There are severe delays on the M25 anti-clockwise approaching Dartford Crossing.
"There's over 8.5 miles of congestion, back to Junction 4.
"Allow plenty of extra time."