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One lane has closed and entry to a slip road is partially blocked after a spillage on the motorway.
The M25 clockwise between junction 2 (A2/Darenth Interchange) and junction 3 (M20/Swanley Interchange) is facing slow traffic due to the incident.
Traffic cameras show vehicles tailing back along the four-lane carriageway.
It is reported the spillage relates to a vehicle losing its load.
According to National Highways, normal traffic conditions are expected from about 7.30pm.
The police has been contacted for more information.