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A man, woman and child suffered life-threatening injuries when their car spun off the A282.
The three, all from the Dartford area, are critical in hospital after the accident on Friday, just before midnight.
A 10-year-old boy, also in the Fiat Punto, had minor injuries in the crash, near to the M25 junction 1B.
There were no other vehicles involved, but police are keen for witnesses to come forward.
If you saw the incident and can help police with their inquiries, please call the Serious Collision Investigation Unit on 01622 798538.