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Rose Gibb will break her silence about the C-diff scandal in a documentary to be screened tonight.
Ms Gibb quit as chief executive of the Maidstone and Tunbridge Wells NHS Trust days before a Healthcare Commission report blamed hygiene failures for two outbreaks of the superbug.
The Healthcare Commission report said 90 people died with the bug during that time, and the trust is now facing compensation claims from many of their families.
Ms Gibb is also suing the trust for a £250,000 severance package.
But throughout the saga, Ms Gibb has refused to comment on the timing of her departure or the criticisms in the report.
At 10.20pm tonight, BBC One's Panorama will broadcast a letter from Ms Gibb during a documentary titled "How clean is your hospital?" about the C-diff outbreaks.
The letter is expected to say that she had to make difficult and unpopular decisions about patient care which she believes reduced risk - and that she did not leave her post willingly.
Former trust chairman James Lee, who is also expected to feature in the programme, said: "I said that I felt, and still feel, personally responsible for what happened.
"But I did also point out that what happened here was happening across the NHS, where about 9,000 people died. There was extreme pressure placed on the trust because of government targets."