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Parts of the M2 motorway are set for full closures because of works to the Medway Bridge.
It is being resurfaced in both directions as well as replacing bridge joints in the London-bound carriageway.
The work will be done by A-one+, on behalf of Highways England, and starts tomorrow running through to the end of November.
A letter sent to residents said: "In order to carry out these works as efficiently and as safely as possible, work will be undertaken under a series of full closures to resurface the road and lane closures to replace bridge joints."
Junction 3-2 of the M2 London-bound, including the J2 off-slip will be closed from tomorrow until Saturday, October 20, from 8pm to 6am.
From Sunday, October 21 to Sunday, October 28, the London-bound J2 off-slip, hard shoulder and lane one will be closed for 24 hours.
The M2 London-bound between J3-2 and the J2 off-slip will be closed from 8pm to 6am between Monday, October 29 and Saturday, November 3.
There'll be disruption until 8am on Friday, November 2, due to lane one being closed between junctions 3 and 2 westbound and the exit slip being shut at 2.
Lanes one and two between junctions 3 and 1 will be closed from 8pm to 6am every day from Friday, November 2, to Sunday, November 4. Lane one at junction 2 will also be closed between 8pm and 6am from Tuesday, November 13 to Thursday, November 15.
Lanes two and three of the M2 London-bound between J2-3 will be closed from 6am to 8pm between Sunday, November 4 and Tuesday, November 13.
Junction 2-3 of the M2 coast-bound and the J2 on-slip is closed between 8pm to 6am from Tuesday, November 20 to Friday, November 23.
In their letter Highways England said there will "inevitably be some noise and disruption" generated by these works, which they apologised for.
They also wrote that "every effort has been made to ensure disruption to nearby residents is kept to a minimum."
Highways England have been contacted for further information.
The westbound motorway will be fully closed between junction 4 and 3 from 8pm to 6am between Friday, November 2 and Sunday, November 5 and again between Tuesday, November 13 and Thursday, November 15.
Lane three of the westbound carriageway at junction 3 will be closed between 8pm and 6am on Wednesday, November 13.
It will also be closed from 3 to 2 from Wednesday, November 14 to Friday, November 16, on Friday, November 23 to Saturday, November 24 and from Monday, December 3, to Thursday, December 6.
There will also be closures on the westbound carriageway between junction 4 and 2 between 8pm and 6am from Wednesday, November 14, to Thursday, January 24 and between junctions 4 and 3 from 9pm on Tuesday, October 30 to 6am on Thursday, November 15.