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People are being warned of parking disruption on the A2 for up to three weeks.
Resurfacing work is being carried out on Watling Street in Strood from October 28.
Medway Council has asked people to find alternative parking arrangements for the duration and said there maybe some periods where people are unable to access their driveways.
The works will be from outside number 77 to Elaine Avenue and outside the petrol garage on the other side of the road to number 26 between 7am and 7pm.
Residents have been asked to ensure any vegetation from their gardens that hangs over the public footway is cut to their boundary.
The council has apologised for any potential noise, and have said every effort will be made to keep the disturbance and site noise to a minimum.