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More than 20 schools are closed or partially closed in Medway today.
Varying levels of disruption are expected across many schools as members of the National Union of Teachers go on strike.
Luton Infants, Luton Juniors and the St Thomas of Canterbury RCP School, with the exception of the morning nursery session, will be closed completely during the day.
Another 20 schools, grammar schools and academies will only be welcoming in a select few of their pupils.
The NUT cancelled its planned one-day strike in November and postponed action in February to continue talks with education minister Michael Gove.
But they say little progress has been made and Mr Gove is not listening to the concerns of teachers.
An NUT spokesman said they would be striking against an "excessive workload and bureaucracy, performance related pay and unfair pension changes".
The National Association of School Masters and the Union of Women Teachers (NAS/UWT) announced last week they will not be taking part in the strike.
Schools in Medway said that while they will endeavour to keep classes running, disruption for some pupils seems inevitable.
Arrangements for the 23 schools which are closed or partially closed:
Teachers will gather at the Three Daws Pub in Gravesend at 10am before another rally at St Thomas' Hall is held in Canterbury at 10.30am.