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Super League Chatham Town SR had Connor Miller (4), Anthoney Uden (2) and Sam Stace to thank for their 7-1 win over Jimmys Giants, whose consolation came from Rob Beer.
Michael Freeman scored both goals in Cliffe Woods Rangers' 6-2 defeat to Medway Sport. Aaron Lorentson (2), Josh Inkpen (3) and Alfie Davey were on target for the victors.
Caleb Dyce (2) and Kieran Trussell goals ensured the points for Medway Rovers 17 in a 3-0 win over Anchorians.
Doubles from James McDonald and Stuart West saw home leaders Quested 4-0 against Bells.
Harry Nash scored both goals for Eagles in their 2-0 victory at Rainham Kenilworth Athletic.
Wigmore and Cuxton 1991 shared the points in a 1-1 draw, Mike Slade for Wigmore and Ted Lay for Cuxton 1991.
In Division 1, Jamie Nash bagged a hat-trick in Omega 92's 3-2 win over Hempstead United. Nick Boyle and David Baker replied for Hempstead.
Rodney Kumukuman scored for Riverside Academy and Jack Burnham replied for Cliffe Woods Colts A in a 1-1 draw.
Previous leaders Swallow Rise 93 lost 3-1 to Anchorians Athletic, Kane Parkes their marksman. Will Mawson with a brace and Taylor Tuck-Brown were on the scoresheet.
George Allan scored the Thamesview goal in their 3-1 reverse to new leaders Milton & Fulston United, James Gasson (2) and Lucin Taravinga were their marksmen.
Division 2 Gillingham Town went down to 10 men after five minutes due to handball on the line but still ran out 5-2 winners over Cantium.
Sean Wicks (2), Ben Silver, Alex Faulkes and Jason Hayes led the 10 men to victory with Brendan Gilbert and Callum Clark on target for Cantium.
Ayo Jimoh, James Hurcomb, Oge Agwu and Michael Hurcomb netted for Medway Invicta in a 4-1 victory over Kent Marina, who replied through Dean Nash.
New leaders Rochester hit 10 without reply against Medway United Central. Michael Curran (4), Declan Cook (2), Lewis Pearce, Tom Stout, Luke Holmes and Jack Rackley did the damage.
In Division 3, Eagles Gold lost 4-3 to Real 60 with John Hickman and Kye Osborne both scoring twice.
Ed King (2) and Simon Tyler goals were not enough for Your Move Chatham as they suffered a 6-2 defeat to Rochester Eagles, whose goals came from Jason Clark, Tom Bicker (2), James Spencer, Liam Green and an own goal.
Kent Marina Gunners shared six goals and the points in a 3-3 draw with Medway Knights in Division 4.
Owen Lampard bagged a hat-trick with Jack Trennary, Dave Wilden and Paul Whittingham netting for the visitors.
Jordan Lorentson scored for Medway Sport XI in their 3-1 defeat to leaders Pegasus 81.
Jake Griffiths bagged a brace for Thamesview Rangers in a 5-2 defeat to Bredhurst Juniors United, whose goals came from Tyler Bell, David Lawanson (2), John Clarkson and Bradley Whitten.