An 82-year-old retired maintenance manager has become the first person in the world to receive the Oxford University and AstraZeneca vaccine outside clinical trials.

Dialysis patient Brian Pinker received the jab at 7.30am on Monday from nurse Sam Foster at Oxford University Hospitals NHS Foundation Trust’s Churchill Hospital.

Mr Pinker, who has been having dialysis for kidney disease at the hospital for a number of years, was pleased to be getting protection against coronavirus.

He said the jab will give him peace of mind as he continues to receive treatment, and he is now looking forward to celebrating his 48th wedding anniversary in February.

“I am so pleased to be getting the Covid vaccine today and really proud that it is one that was invented in Oxford,” Mr Pinker said.

“The nurses, doctors and staff today have all been brilliant and I can now really look forward to celebrating my 48th wedding anniversary with my wife Shirley later this year.

“The vaccine means everything to me, it’s the only way I’ll be getting back to normal life. This virus is terrible, isn’t it?

“They should (get vaccinated). I mean it’s a no-brainer. They need to come, don’t they?

“I’m very pleased that I’ve got the Oxford vaccine, very pleased. I was a bit daunted by it, really. It took me long enough to be a star, didn’t it?”

Alongside Mr Pinker, music teacher and father-of-three Trevor Cowlett, 88, and Professor Andrew Pollard, a paediatrician working at the Oxford University Hospitals NHS Foundation Trust who also pioneered the Oxford jab, were among the first to be vaccinated.

Chief nurse Ms Foster said: “It was a real privilege to be able to deliver the first Oxford vaccine at the Churchill Hospital here in Oxford, just a few hundred metres from where it was developed.

“We look forward to vaccinating many more patients and health and care staff with the Oxford vaccine in the coming weeks which will make a huge difference to people living in the communities we serve and the staff who care for them in our hospitals.”

Hundreds of new vaccination sites are due to open this week, joining the 700 which are already in operation, to administer the first 500,000 doses of the new vaccine.

The first Oxford/AstraZeneca vaccinations will be delivered in Oxford and five other hospital trusts – two in London, and others in Sussex, Lancashire and Warwickshire – to allow for monitoring before the bulk of supplies are sent to hundreds of GPs later this week.

NHS medical director Professor Stephen Powis said: “The NHS’ biggest vaccination programme in history is off to a strong start, thanks to the tremendous efforts of NHS staff who have already delivered more than one million jabs.

“Throughout the pandemic their response has been phenomenal, from introducing world-leading treatments for coronavirus which have saved patients’ lives as well as delivering the very first Covid-19 vaccines outside of a trial in a landmark moment in history, and now rolling out the new Oxford/AstraZeneca vaccine, chalking up another world first that will protect thousands more over the coming weeks.”

Health Secretary Matt Hancock said: “This is a pivotal moment in our fight against this awful virus and I hope it provides renewed hope to everybody that the end of this pandemic is in sight.”

Prof Pollard, director of the Oxford Vaccine Group and chief investigator of the Oxford Vaccine Trial, added: “It was an incredibly proud moment for me to have received the actual vaccine that the University of Oxford and the AstraZeneca teams have worked so hard to make available to the UK and the world.

“As a paediatrician specialising in infections, I know how important it is that healthcare workers along with other priority groups are protected as soon as possible – a crucial role in defeating this terrible disease.”

Last week, regulators and the four UK chief medical officers announced that the gap between first and second doses of the Pfizer vaccine should be lengthened so that more people can be protected faster.

Second doses of either vaccine will now take place within 12 weeks rather than the 21 days that was initially planned with the Pfizer/BioNTech jab, following a change in guidance which aims to accelerate immunisation.

This has been defended by the UK’s four chief medical officers following criticism, including from the British Medical Association (BMA).

The doctors’ union said it was “grossly and patently unfair” for at-risk patients whose imminent second jab appointments would now be rescheduled.

The Oxford/AstraZeneca jab is easier to transport and store than the Pfizer/BioNTech vaccine, which needs cold storage of around minus 70C.

Because it can be stored at fridge temperatures, between two and eight degrees, it is easier to distribute to care homes and other locations across the UK.