Job losses will be “part of the process” according to a Government minister, as the furlough scheme comes to an end.

Chief Secretary to the Treasury Simon Clarke told Sky News: “Obviously there will be a variety of outcomes, I don’t have an estimate with me today. There will be some job losses.”

He added: “Furlough has protected 11.6 million jobs in total … at some point you have to end these emergency measures.

“People’s jobs will be created just as some have very sadly been lost, that is part of the process of ending this crisis and going back to normal.”

The minister also claimed: “We never said we could protect every job … I think we need to be totally honest about this, the Covid pandemic has taken a toll on our economy, it’s changed some things,” he said.

“My message to people would be there are these opportunities there.”

His comments come as the £70 billion furlough programme closes on Thursday after supporting millions of UK workers over the past 18 months.

Uncertainty remains for the future of almost one million workers who were expected to be still receiving support through the financial scheme at the end of September, according to the latest Office for National Statistics (ONS) estimates.

Economists have warned that although many may find work in recovering sectors such as hospitality and travel, there is also likely to be a rise in unemployment due to new redundancies.

The Department for Work and Pensions announced a new £500 million scheme to help vulnerable households over winter.

Alan Custis, head of UK equities at Lazard Asset Management, said the rate of unemployment, which dropped to 4.6% last month, is likely to swing higher again.

“There will also be a percentage who choose retirement over returning to work, but we would expect the unemployment rate to settle at around 5% for the year end, before falling in 2022,” he said.

Mr Custis added that other countries, such as the US and Australia, saw unemployment spikes when similar financial support for workers came to an end.

The end of furlough also comes amid record UK vacancy figures, with the latest ONS data for August reporting more than one million available jobs for the first time on record.

There have also been significant hiring sprees amid labour shortages for HGV drivers, warehouse staff and food production workers.

Nevertheless, Samuel Tombs, chief UK economist at Pantheon Macroeconomics, said he has “doubts” as to whether broader consumer demand will have jumped enough by October to re-employ all staff who remained on furlough.

As a result, the Liberal Democrats have called for furlough support to be extended for the 10 most affected sectors to avoid a “tidal wave” of job losses.

In a letter to Chancellor Rishi Sunak, Liberal Democrat Treasury spokesperson Christine Jardine said furlough should be extended for another six months for the 10 sectors, which include air travel and photography, in a move it claims would cost around £600 million.

Ms Jardine said: “The withdrawal of furlough risks having a devastating impact on countless families already facing a winter of soaring energy bills.

“The Government needs to rethink its approach or the country could face a Coronavirus Black Thursday.”

However, leaders at trade bodies for heavily impacted sectors are now looking beyond the furlough scheme to appeal for policy reform in other areas.

Kate Nicholls, chief executive of UKHospitality, said: “With businesses currently experiencing a record number of vacancies, our hope is that those seeking employment will consider the varied and exciting opportunities a career in hospitality offers.

“With the right support and conditions, the sector has the potential to be at the forefront of the economic recovery.

“In order to drive further job creation, we urge Government to implement a long-overdue reform of business rates and a permanently lower rate of VAT for hospitality and tourism in order to help fragile businesses back on their feet.”

Tom Ironside, director of business and regulation at British Retail Consortium (BRC), said: “As Government ends the furlough scheme, the industry’s attention is turned towards other pressing priorities.

“First and foremost is the need for Government to deliver on its manifesto promise to bring down the business rates burden to sustainable levels.

“Additionally, to support the many people coming off furlough, the Government should turn the Apprenticeship Levy into a wider Skills Levy to provide greater scope to retrain existing workers through shorter, high-quality skills courses.”