Former chancellor and home secretary Sajid Javid will replace Matt Hancock as Health Secretary, Downing Street has announced.

The appointment came the day after video footage emerged of Mr Hancock kissing an aide in his ministerial office in a breach of coronavirus restrictions.

Images and video showed Mr Hancock in an embrace with aide Gina Coladangelo last month, and the former Health Secretary was facing increasing pressure to quit which came to a head on Saturday when he gave Boris Johnson his resignation.

In a letter to the Prime Minister, Mr Hancock said: “The last thing I would want is for my private life to distract attention from the single-minded focus that is leading us out of this crisis.

“I want to reiterate my apology for breaking the guidance, and apologise to my family and loved ones for putting them through this. I also need to be with my children at this time.”

He said: “We owe it to people who have sacrificed so much in this pandemic to be honest when we have let them down as I have done by breaching the guidance.”

He paid tribute to NHS staff and Department of Health and Social Care (DHSC) officials and admitted that “we didn’t get every decision right”.

But he said: “I know people understand how hard it is to deal with the unknown, making the difficult trade-off between freedom, prosperity and health that we have faced.”

In a video posted on Twitter, Mr Hancock said: “I understand the enormous sacrifices that everybody in this country has made, you have made. And those of us who make these rules have got to stick by them and that’s why I’ve got to resign.”

Various outlets including the BBC, The Sunday Mirror, and The Sunday Telegraph reported that Mrs Coladangelo would also be leaving her DHSC job, but the department had not confirmed this on Saturday night.

A statement from 10 Downing Street released around 90 minutes later said: “The Queen has been pleased to approve the appointment of the Rt Hon Sajid Javid MP as Secretary of State for Health and Social Care.”

Mr Javid tweeted: “Honoured to have been asked to serve as Secretary of State for Health and Social Care at this critical time.

“I look forward to contributing to our fight against the pandemic, and serving my country from the Cabinet once again.”

In response to Mr Hancock’s letter, the Prime Minister wrote: “You should leave office very proud of what you have achieved – not just in tackling the pandemic, but even before Covid-19 struck us.”

And he said: “Above all, it has been your task to deal with a challenge greater than that faced by any of your predecessors, and in fighting Covid you have risen to that challenge – with the abundant energy, intelligence, and determination that are your hallmark.”

Mr Hancock had caused problems for the PM as Conservative MPs began to break ranks to call for Mr Hancock to go.

But Mr Johnson’s history with his replacement is not without controversy.

Mr Javid quit as Chancellor in February last year after he said Mr Johnson set conditions “any self-respecting minister” would reject during a Cabinet reshuffle.

You should leave office very proud of what you have achieved – not just in tackling the pandemic, but even before Covid-19 struck us

At the time, the Prime Minister ordered Mr Javid to fire his closest aides and replace them with advisers chosen by Number 10 if he wanted to remain in post – conditions he said he was “unable to accept”.

Mr Javid chose to quit instead and was replaced by his former deputy at the Treasury, Rishi Sunak.

Mr Javid had also clashed with the PM’s former chief adviser Dominic Cummings.

In August 2019, Mr Cummings had fired Mr Javid’s aide Sonia Khan, who later settled a claim for unfair dismissal with the Government.

Labour’s shadow health secretary, Jonathan Ashworth, said: “Sajid Javid failed to reverse the previous eight years of social care cuts or deliver the investment our NHS needed in his time as chancellor of the Exchequer.

He now needs to explain how he will bring down sky-high waiting lists, ensure people get the cancer care they need, get young people vital mental health support and crucially fix social care, which has suffered swingeing cuts under the Conservatives

“He now needs to explain how he will bring down sky-high waiting lists, ensure people get the cancer care they need, get young people vital mental health support and crucially fix social care, which has suffered swingeing cuts under the Conservatives.”

Earlier, veteran Tory Sir Christopher Chope said his constituents were “seething” over the events which led to Mr Hancock’s resignation.

North Norfolk MP Duncan Baker said: “In my view people in high public office and great positions of responsibility should act with the appropriate morals and ethics that come with that role.”

Mr Johnson had refused to sack Mr Hancock, with his spokesman saying the PM considered the matter closed after receiving the West Suffolk MP’s apology on Friday.

Labour leader Sir Keir Starmer tweeted: “Matt Hancock is right to resign. But Boris Johnson should have sacked him.”

Liberal Democrats’ leader Sir Ed Davey tweeted: “Matt Hancock’s legacy as Health Secretary will be one of cronyism and failure.

“And the fact that Boris Johnson thought Hancock could just carry on regardless brings the Prime Minister’s judgement into question once again.”

Mr Hancock’s three-year tenure as health secretary came to an end after The Sun newspaper published stills of what appeared to be CCTV footage from inside his ministerial office of him kissing Ms Coladangelo.

Ms Coladangelo, a friend from Mr Hancock’s days at Oxford University, was brought into DHSC as an unpaid adviser last year before being given the £15,000-a-year role of non-executive director in the department.

Legislation in place at the time said that “no person may participate in a gathering” that “consists of two or more people… and takes place indoors”.

An exception to this rule was that the gathering was “reasonably necessary for work purposes or for the provision of voluntary or charitable services”.

Tory MPs and ministers will also have been eyeing the by-election in Batley and Spen next week.

Christchurch MP Sir Christopher told the BBC the impact on the West Yorkshire vote was on his mind.

Labour MP for Halifax, Holly Lynch, had been preparing to write an open letter to Conservative MPs and the Tory candidate in the election, Ryan Stephenson, challenging them to tell Mr Hancock to resign.

Before he did, Sir Christopher told Radio 4’s PM programme: “Of course I feel that. And that’s another reason why I think that the sooner he goes the better, because otherwise the last few days of the campaign are going to be dominated by this issue and it’s obviously not going to be very helpful for the Conservatives.”

North West Leicestershire Conservative MP Andrew Bridgen told Sky News it had been an issue on the doorstep while campaigning in the constituency.