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Scientists explore whether mistletoe could be used as surgical glue

PA News

Scientists are exploring whether mistletoe could be used as a surgical glue.

Researchers from the University of Essex have grown the festive plant in controlled laboratory conditions and are studying its genetic make-up.

Dr Nick Aldred, of the School of Life Sciences, said mistletoe’s potential as a glue has been “known about for thousands of years”.

As far back as 50BC the Roman author Pliny described the use of mistletoe berries in the creation of birdlime, which is used to trap birds in hunting.

Dr Pallavi Singh and Dr Nick Aldred in the lab as they research whether mistletoe could be used as a surgical glue (University of Essex/ PA)
Dr Pallavi Singh and Dr Nick Aldred in the lab as they research whether mistletoe could be used as a surgical glue (University of Essex/ PA)

During the Second World War, birdlime was also used to create British sticky bombs.

However, the commercial and medical use of mistletoe-based glue has not been fully explored due to uncertainty about the exact adhesive mechanisms and availability of berries on a large scale.

Dr Aldred said: “By exploring the natural world to create environmentally-friendly glues, we can use naturally-occurring materials to benefit us all.

“It might seem unusual to use mistletoe berries as the basis of a glue, but its potential has been known about for thousands of years.

A mistletoe berry being squeezed as scientists explore whether the plant could be used as a surgical glue (University of Essex/ PA)
A mistletoe berry being squeezed as scientists explore whether the plant could be used as a surgical glue (University of Essex/ PA)

“If we can develop and build on this knowledge, hopefully we can make a useful glue – whilst learning more about how nature can benefit us all.”

Dr Pallavi Singh, who is working alongside Dr Aldred, said mistletoe is “really understudied” and “could have a wide range of uses – including high-quality surgical glue”.

“Mistletoe also has the largest genome of any plant to be sequenced in the UK, meaning the research could have wide-ranging impacts in biotech and how we understand the world,” she said.

The research is in its early stages, with a series of experiments to follow as the project develops to see if mistletoe and mistletoe-inspired glue can be developed commercially.


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