Surge vaccinations in the regions worst hit by the Indian variant of coronavirus may go ahead after talks between council leaders and the Government.

The leader of Bolton Council said there had been discussions with the Government about the introduction of vaccines for younger age groups and suggestions were it would be progressed as soon as possible.

Asked about surge jabs, David Greenhalgh told BBC Radio 4’s The World at One: “This is an issue of capacity but we have had very, very constructive talks and certainly all the soundings are is that they are looking to progress that as soon as possible.

“The vast majority of our cases are in their teens, 20s and 30s at the moment.

“If we can get vaccinations to (those aged) 16-plus, which are licensed by Pfizer, then it will make a total transformation of transmission as it moves forward.

“I think realistically that would start in targeted areas where we see the predominance (of the virus) currently.”

London and the North West have seen the biggest rise in cases of the variant, with Public Health England (PHE) data showing it has been responsible for four deaths as of May 12.

The Government has been looking at ways to “flex” the rollout of vaccines in the worst-hit areas, including possibly vaccinating everyone in multi-generational households from 18-year-olds to grandparents.

More vaccine doses have been sent to Bolton, which has a particularly high rate of the Indian variant, while 800,000 PCR tests have been sent to 15 separate areas of England, including parts of London and Merseyside.

Another option on the table is bringing forward the date for second doses of vaccine for the elderly and vulnerable in worst-affected areas.

Earlier, the vaccines minister said the public must help suppress the Covid-19 infection rate if the planned lifting of restrictions in June is to stay on track.

Nadhim Zahawi urged people in affected areas to follow local health advice, get tested and isolate if they test positive.

Asked if the June 21 road map easing – when all legal limits on social contact are due to be lifted – could be put on ice, Mr Zahawi told LBC’s Nick Ferrari that this Monday’s reopening of indoor meet-ups “is still on”.

When pressed on whether the plans for June 21 could be paused, he said: “The way we don’t have to do that is by everybody doing their bit, by taking the two tests a week, doing your PCR test in those areas, and to isolate, isolate, isolate.

“We have got to break the cycle of infection, because one of those big tests was infection rates have to be suppressed, and the other big test is variants.

“If those cause a problem, then the tests will fail. The four tests have to be met for June 21.”

Mr Zahawi said the seven-day rolling average figures for infection show a 12.4% rise, but hospital admissions are down by 7.9%.

“That is good news because it tells you that the vaccines are clearly working in terms of hospitalisation and severe infections… but the infection rate is what is concerning, which is why we have to surge test and then isolate,” he said.

Asked on BBC Breakfast what is stopping vaccines being given to younger age groups in affected areas now, Mr Zahawi said it takes three weeks to build protection from a first dose and to have any effect on transmission of the virus. This suggests surge vaccines may not take effect quickly enough.

Bedford Borough Council has been among those calling for vaccines to be made available for over-16s in the face of the variant.

Greater Manchester Mayor Andy Burnham also told BBC Breakfast: “We do say to the Government they do need to go further now and allow those extra vaccine supplies to be used in vaccinating the younger working-age population, the student population.

“That is what is needed if we are to make the most decisive and effective intervention into this situation that we can right now.

“We recognise the pressure on vaccine supplies all over the country but we have been moving at a pace where we have been treating all areas equally, and I think the time has now come to recognise areas with the highest case rate do need to be able to move more quickly down the ages.”

He said there are “younger people in places like Bolton who are in quite insecure work, so if they become ill they fear they won’t be paid if they have to take time off work” for self-isolation.

He said he does not support local lockdowns which “really didn’t work” last year, adding: “We are in a different situation this year because, even though we are seeing spread of the Indian variant in Bolton, we are not seeing the same numbers of people going into hospital because obviously older people are more protected now.

“So we don’t need to have the same response that we had last year. We do believe if we move quickly on vaccination we can take away any risk of a local lockdown.”

It comes after the Prime Minister said on Thursday there is “nothing that dissuades me” from easing England’s lockdown on Monday, or the further steps towards normality on June 21.

But he added “there may be things we have to do locally and we will not hesitate to do them if that is the advice we get”.

There is no current evidence that vaccines do not work against the Indian variant.

A PHE report published late on Thursday suggests the transmissibility of the Indian variant is similar to the Kent variant and may be slightly higher.

Cases of the Indian variant are also growing at a faster rate than for the Kent variant.

There are also a small number of potential reinfection cases but PHE said this is to be expected for the main variants.

Paul Hunter, professor in medicine at the University of East Anglia, said the planned June 21 lockdown lifting could be in doubt if the Indian variant causes increases in cases in elderly people and a rise in people needing hospital care.

He told BBC Radio 4’s Today programme: “I think the big question is how many of people who are getting the Indian variant will end up requiring hospitalisation?

“And at the moment the hospitalisation rate doesn’t seem to be increasing yet, although if this becomes much more common we’ll almost certainly see some increase, so I think it’s certainly a concern.

“I think the step four is in doubt in June now, but we really need to see what impact it has on severe disease before we can really be certain.”