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A 30-year-old motorcyclist was taken to hospital with serious back injuries after his machine was in collision with a car.
The crash happened in Shoreham Lane, Tenterden, near Ashford, at about 8.15am on Tuesday.
The rider of the Kawasaki motorcycle, a local man, was taken to a London hospital.
The driver of the Vauxhall Corsa car, also a local man, was not injured.
Kent Police's Serious Crash Investigation Unit attended the scene initially, and the road was closed until about 12.45pm.
Anyone with information about the collision is asked to contact PC Steven Barker on 07870 252488.