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Margate picked up their first Isthmian Premier win under caretaker bosses Ben Greenhalgh and Reece Prestedge.
They beat Wingate & Finchley 3-1 at Hartsdown Park to maintain their seven-point cushion over the bottom four.
Sam Blackman and Ade Cole gave the hosts a half-time lead and while Dernell Wynter pulled one back, Phil Roberts made the game safe for 16th-placed Gate.
In-form Folkestone suffered a shock 3-2 defeat at struggling Brightlingsea Regent.
Ibrahim Olutade cancelled out Tom Richardson’s opener before half-time and Ira Jackson edged the visitors in front.
But Suleyman Zudhu made it 2-2 and Zack Littlejohn won it for Brightlingsea with two minutes left.
Cray Wanderers lost top spot, dropping to third place after a 2-2 draw at home to Lewes.
Tom Derry and Dajon Golding put Neil Smith’s side in charge but Ryan Gondoh and Joe Taylor rescued a point for the visitors in the second half.
Chatham are the new leaders in Isthmian South East after goals from Ike Orji, Emmanuel Oloyede, Seidou Sanogo and Jack Evans (penalty) in a 4-1 win at Ashford.
They move above Ramsgate, who lost 2-0 at Three Bridges.
Steve Lovell’s side trailed at the break to a Curtis Gayler strike, and it was former Margate striker Noel Leighton who added the second.
Sheppey’s five-match winning streak ended as they were held to a 1-1 draw by battling Corinthian.
Connor Wilkins put the Ites in front but Saw Bewick quickly levelled.
Sevenoaks boosted their play-off bid with a 3-1 home win against East Grinstead.
Kieran Cadogan gave Oaks a half-time advantage and Solomon Baugh and David Kawa secured the points after Matthew Daniel levelled.
Liam Smith scored the only goal just past the hour mark as Hythe beat play-off hopefuls Whitehawk 1-0 at Reachfields.
Cray Valley’s long unbeaten run is over after a late defeat at Littlehampton.
The promotion-chasing Millers suffered a first loss in 13 games, with Josh Short scoring the only goal in the 89th minute.
Ryan Maxwell suffered his first defeat as Sittingbourne manager, with the Brickies going down to Louis Theophanous’ second-half strike at Beckenham.